oligonucleotides

The Rochester team used a synthetic molecule – called an antisense morpholino oligonucleotide – that mimics a segment of the genetic code.

The double-stranded oligonucleotides are designed with 5´ OH blunt ends, making them easily labeled to high specific activity with T4 polynucleotide kinase.

Oligonucleotide synthesis is a common technique in molecular biology.

Researchers use oligonucleotide probes to detect specific DNA sequences.

PCR amplification often requires oligonucleotide primers.

Sequencing technologies rely on oligonucleotide hybridization.

Oligonucleotide therapeutics are being developed for various medical applications.

The design of oligonucleotide primers is crucial for PCR success.

Antisense oligonucleotides can inhibit gene expression.

Oligonucleotide microarrays are used for gene expression profiling.

Oligonucleotide labeling is important for tracking nucleic acids.

Oligonucleotide-based therapies show promise in treating genetic disorders.